you know the engine in the nsx sits sideways right? how do you expect to fit a straight 6 along with a custom transaxle sideways into a nsx body?
that alone would shoot your idea down the drain. now if you would swap in a SR20DET or a 4G63 thats a more interesting swap. you'll have a lighter engine that can hold 500whp and can rev higher than the C30a.
This all depends on how deep your pockets are. The LeMans NSX has a vertically mounted engine with twin turbos cranking over 600 HP. But assuming that your don't have a $100,000+surplus, I highly doubt your gonna be getting a straight 6 to fit right.