New window regulators are a fix; but, new regulators are the exact same design as your old regulators and will over time become just like your old regulators.
The guides are a wear item. I would be inclined to give the combination of the SOS guides, a good cleaning of the regulator track and the application of the ridiculously expensive Honda Urea grease a go. Compared to the cost of new regulators its a low risk venture. You have to pull the doors apart to do either clean up of the regulators or replacement of the regulators. Once the old regulators are out, I probably spent an average of 1.5 hours to install my Hugo kit in each regulator (longer on the first, quicker on the second). If you are just doing the guides it should go much quicker. While its out, do check to make sure that the track for the regulator has not become bent - you will find a couple of posts dealing with this problem.
The Hugo kit improves the operation of the regulators. Compared to newer cars, the NSX windows are still slow; but, with the kit they are not as slow and operation is much smoother and quieter. However, just like the original windows it will be important to insure that the track remain clean and lubricated (the all important Urea grease). Hugo no longer appears to be active with kit production; however, I suspect that there were more kits purchased than installed because of the effort to do the install. I drove around with my kit in the trunk for a couple of years before finally getting motivated to install it. If you post an add in the wanted to buy parts section of Prime you might find someone who has the kit; but, does not want to do the installation.
Whether you do a complete Hugo kit or just guide replacement, do get the urea grease. Also, if you do this and clean up everything, make sure that you lubricate the little spool where the regulator attaches to the holder on the glass. I did my Hugo kit, reinstalled the regulator and did a test run and ended up with a loud 'pop' noise during operation of the window. There is a Honda TSB 93-004 that describes this noise and the fix. Simple lubrication of the spool so that it slides back and forth easily prevents the pop. Easy to do with everything out of the door - a pain if you discover the problem after you have put the door liner back on.
If you have a 1991 or 1992 NSX, there were some design issues with those regulators. Apparently there was a recall / good will replacement? Check to make sure that you don't still have one of those early regulators. If you do, then outright replacement would be the better option.
Final word of caution, unless you are sure that you have a glass alignment problem, do not mess with the alignment of the door glass in order to try and improve things. If you think pulling the regulator apart to replace the guides is significant effort, its minor in comparison to aligning the glass the correct way as set out in the service manual.