As with anything in life, FI is a series of compromises. If you are looking for plug and play (for the most part) a low boost CTSC checks many boxes. But if you are looking for more power than the stock OEM setup, and let's face it, if you are looking into SC or turbo you ARE looking for more than a little more power, you are looking at high boost SC or turbo(s). More power requires more safeguards to make sure your car stays together. You will be looking at control over your ECU or going stand alone. You will be require to rework your fuel management with larger injectors and possibly a fuel pump with more capacity. You will want to add some type of cooling to the charge air or suffer heat soak or worse. You are going to want to install a system that monitors all of this and safeguards your engine, Going FI is not for the faint of heart and will cost some money.
There are many proven systems out there and reliability has greatly improved with better understanding of the different options and better equipment available. A lot of my friends are very happy with their CTSC and around 350 to 400 rwhp. But the whine, constant boost and fuel consumption, and heat soak were factors that steered me toward turbos.
For those seeking big power, the fad was for a big single turbo. This would put tremendous pressure upon engine and transmission parts that the stock NSX drivetrain was not engineered to handle. That is why we have heard/read of some catastrophic failures. But knowing the compromises and planning to minimize the cons, will point you in the right direction. I wanted more power than what the CTSC could produce. I also wanted it to be bulletproof and not have to worry about having to tune it every time I turned around. So I went with two smaller turbos, stand alone engine management and water to air intercooler to keep the charge air under control. I have torque, horsepower and I don't have to fiddle with it. And the power is very predictable with no noticeable lag at lower rpm's. Is it a V-8? No. But it is very fast and predictable and it will stay together for a long time.