I have never driven a coupe, so my comments are from a Targa only standpoint...
When roof is on, there is much less (if any) "jiggle" of the windshield/A pillars...mostly noticeable and easy to contrast to when the roof is off when on a particularly rough road with numerous small bumps and you see the rear view mirror with little vibrations in it
When on, I can't really notice these at all, as the roof obviously acts as a method of bracing entire windshield.
The roof on off process - easy, and less than 15 seconds...only way it could be simpler is if you had someone else do it for you and you stayed in the car...
I almost never drive with it on-up here on Canada, the car is driven in summer only, thus roof is almost always off to enjoy the summer..wind noise is more pronounced of course on the highway, but can't beat the feeling around town with windows down, and roof off.
STMPO rear strut bar - very noticeable difference from OEM, the first thing I noticed on my first drive after changing it. No question it makes a difference....
If indeed a coupe is more stiff (and logically it would be) , its not that the Targa is not stiff, its just the coupe is "more" stiff... other than the little jiggly rear view mirror, you wouldn't notice a thing
As many have said, unless you plan on driving car hard at the track, you would not be dissappointed with Targa...at least you have an option to remove or not....with coupe, no choices
I really enjoy the flexibility I have with a Targa...
there's my (biased) opinion...