It depends on a lot of things, weight, size, spoke design. a bigger rim usually weight more, requires bigger tires, there fore moere weight, and will increase the overall diameter, which will have the same effect as having longer gears. So if you take into account the 5 effects of bigger wheels:
1)heavier(bad for acceleration)
2)heavier rotational weight(even worse for acceleration)
3)bigger tires(very heavy, bad for acceleration again, and it will increase the effect of point 1 and 2)
4)heavier unsprung weight(bad for handling)
5)increase the final drive ratio(make your car rev slower, bad for acceleration)
Now do you still want those 19inch lead weights? I dont mean to scare you off on rim upgrade. There are many benefits such as they clear aftermarket big brakes, they can accept wider tires therefore increase your grip. And there are also some very high quality rims that are extremly light, such as the TE-37 I have on my car, they weight even less than the stock 15/16inch rims in 17/18 size!
It's just a bad choice to get rims as big as 18/19 for the NSX, unless you must have that pimpin look, in that case, you chose the wrong car
George Wang
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http://www.geocities.com/Tokyo/Dojo/6073/index.html